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How To Apply Class 6.2 Infectious Substance Labels For Ground And Air Shipments

Updated October 16, 2026
Published October 16, 2026
William Carlin

Class 6.2 Infectious Substance Label

Definition

A dangerous-goods hazard label used to communicate the transport hazard classification represented by 'Class 6.2 Infectious Substance Label'.

Overview

Class 6.2 Infectious Substance Label A dangerous-goods hazard label used to communicate the transport hazard classification represented by 'Class 6.2 Infectious Substance Label'.


Applying a Class 6.2 label correctly is a routine but compliance-critical task for shippers, warehouse teams, and couriers. Label errors are a common cause of carrier refusals and regulatory enforcement. This article provides step-by-step guidance for labeling infectious substance packages for both ground and air transport in the United States while highlighting mode-specific differences and practical checks that reduce rework.


Step 1: Confirm Classification (Category A vs B)


Start by determining whether the material meets Category A criteria (capable of causing severe disease) or Category B (lower risk, shipped as UN 3373). Use laboratory results, organism identification, and guidance from PHMSA/IATA to make the call. When in doubt consult your institution’s biosafety officer and retain documentation of the classification decision.


Step 2: Select Approved Packaging


Packaging must meet UN performance standards. Typical requirements include triple packaging: primary receptacle(s), leakproof secondary packaging, and an outer packaging with sufficient strength for transport. For Category A, UN certified packaging and specific performance tests are mandatory. For Category B (UN 3373), packaging must meet basic integrity requirements but the UN performance standard is different.


Step 3: Choose The Correct Labeling And Markings


Label selection differs by category and mode:


  • Label: Category A—apply the Class 6.2 diamond with the appropriate UN number (for example UN 2814 or UN 2900), affix the proper shipping name if required, and include the Shipper’s Declaration for Dangerous Goods for air carriage.
  • Label: Category B—mark the outside of the package with the UN 3373 designation and ‘‘Biological Substance, Category B’’; many carriers require a UN 3373 label rather than the full Class 6.2 diamond.
  • Label: Include handling labels where required (e.g., temperature control or orientation arrows) but do not obscure the hazardous-goods markings.


Step 4: Mode-Specific Considerations


Air transport imposes stricter rules than ground:


  • Label: Air shipments of Category A require a completed Shipper’s Declaration for Dangerous Goods and compliance with IATA DGR, which specifies label size, placement, and additional documentation.
  • Label: Many passenger aircraft restrictions disallow certain infectious substances or require special acceptance procedures; carriers may need advanced notice and booking with a specialized cargo desk.
  • Label: Ground couriers following DOT rules still require proper marking, but documentation is generally less complex for Category B shipments moved by surface transport within the U.S.


Step 5: Complete Documentation And Carrier Acceptance


Documentation varies by category and mode. For air Category A shipments, the Shipper’s Declaration is essential; for Category B, a simple packing list and UN 3373 marking may suffice. Always verify carrier-specific acceptance procedures and whether pre-approval or special handling codes are required. Keep copies of paperwork and the classification rationale on file for inspections.


Step 6: Apply Labels Correctly And Verify


Label placement and integrity checks reduce inspection failures:


  • Label: Affix the label flat on a main surface of the outer packaging where it is unobstructed and readable; labels must meet minimum dimension requirements set by regulators and IATA.
  • Label: Use durable labels resistant to moisture and abrasion; avoid placing labels over seams or closures.
  • Label: Verify that UN numbers, shipping names, and emergency contact details are correct and legible.


Operational Checklist For Dispatch Teams


  • Label: Classification confirmed and documented (Category A vs B).
  • Label: Packaging meets UN or carrier requirements and shows no damage.
  • Label: Correct label(s) and UN markings applied to outer packaging.
  • Label: Required documentation completed and carrier acceptance confirmed.
  • Label: Emergency contact information included on paperwork and package if required.


In short, the Class 6.2 Infectious Substance Label must be applied according to classification, packaging, and mode-specific rules. Use a firm checklist, confirm carrier requirements, and maintain training for staff to avoid refusals and preserve safety during both ground and air transport.

Sources And Additional Reading (3)

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